Clinical and Radiographic Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft for Management of Periodontal Intrabony Defects: a Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Clinical attachment level
研究概览
简要总结
A clinical and radiographic evaluation of 2 regenerative techniques, bioresorbable membrane and bone allograft for management of periodontal intrabony defects.
详细描述
Twenty-two patients suffering from advanced chronic periodontitis were included in this randomized controlled clinical trial. Each subject contributed had two- or three-walled intrabony defects. Patients were randomly assigned into two groups; bioresorbable membrane or bone allograft. Clinical parameters were recorded at baseline and at 3 and 6 months postoperatively. Radiographic parameters were recorded at baseline and at 6 months postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Severe chronic periodontitis patients.
- •having at least one site with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss as detected in periapical radiographs.
排除标准
- •Pregnant women
- •Having any given systemic disease
- •Taking any type of medication and/or antibiotic therapy during the 3 months before the study
- •Received periodontal treatment within the past 12 months Current or former smokers
结局指标
主要结局
Clinical attachment level
时间窗: change from Baseline at 6 months
Change from baseline in clinical attachment level in mm in chronic periodontitis patients
次要结局
- bone defect area(Baseline and 6 months)
- pocket depth(Baseline and 6 months)
研究者
Noha Ayman Ghallab
Professor of Oral Medicine and Periodontology
Cairo University