IRCT20201116049408N1招募中2 期
Comparing the effects of once versus twice intracoronary injection of allogenic Wharton's jelly derived mesenchymal stem cell in improving ejection fraction of patients with post myocardial infarction moderate to severe reduced ejection fraction
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 60 years（—）
- 性别
- All
入选标准
- •Ages20- 60 Years
- •Genders: Both
- •First MI within 3 to 5 days
- •Post AMI LVEF less than 40% as assessed by echocardiography
- •Negative pregnancy test ( in women with childbearing potential )
排除标准
- •History of prior anterior myocardial infarction
- •Patients with regional wall motion abnormalities in the non-infarct region
- •Patients with significant valve disease; defined as stenosis or regurgitation graded as greater than moderate (2+)
- •Patients with another etiology of LV dysfunction (known/suspected non ischemic cardiomyopathy, previous anthracycline therapy, known ethanol abuse (greater than 6 oz. ethanol/day on a regular basis).
- •Poor echocardiography window
- •Active infection or history of recurrent infection or positive test for syphilis (RPR), hepatitis B and C (HBsAg, Anti-HCV), HIV and HTLV-1
- •Documental Terminal illness or malignancy
- •Previous bone marrow transplant
- •Autoimmune diseases
研究者
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