Percutaneous Coronary Angioplasty Compared With Exercise Training in Symptomatic Coronary Artery Disease
Phase 2
- Conditions
- CADStable Angina Pectoris
- Registration Number
- NCT00176358
- Lead Sponsor
- University of Leipzig
- Brief Summary
The purpose of this study is to compare coronary angioplasty with stent implantation with an exercise rehabilitation program in patients with stable coronary artery disease (CAD).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
- Angiographically documented CAD, with at least one coronary artery stenosis of more than 50% in a native segment never subjected to intervention, which is recommended for treatment with percutaneous transluminal coronary angioplasty (PTCA).
- Stable coronary artery disease
- Eligible patients could be asymptomatic or have class I to III angina (Canadian Cardiovascular Society [CCS]) with documented myocardial ischemia
- Angina pectoris threshold > 50 Watt (cycle ergometry)
- Permanent residence should be within 25 km of training facility.
Exclusion Criteria
- < 18 or > 70 years of age
- Patient currently participating in an exercise training program
- Unstable angina pectoris or myocardial infarction during the last 2 weeks
- Symptoms of CCS class IV
- Exercise limitations due to clinical conditions not related to CAD
- Left ventricular ejection fraction (LVEF) of < 40%
- Ventricular arrhythmia (Lown Ivb)
- Hemodynamically significant valvular heart disease
- Previous cardiac surgery
- PTCA performed during the last 12 months
- Any major non-cardiac condition that would adversely affect survival during the duration of the study
- Reduced compliance
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Leipzig - Heart Center
🇩🇪Leipzig, Germany