Evaluation of the effect of Gaznab herbal product on the control of primary hypertensio

Phase 3

Recruiting

Conditions: Hypertension.
Essential (primary) hypertension

Registration Number: IRCT20210622051660N1

Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 36

Inclusion Criteria

Men and women aged 30-65 years
Hypertension grade1 with pressure equal to or greater than 140.90 mmHg to 159.99 mmHg
Are treated with a blood pressure medication (one to three drugs based on the protocol).
BMI greater than or equal to 27
At least one month has passed since starting the medication
The person should not be at high risk (diabetes mellitus and end organ damage , etc.)

Exclusion Criteria

History of hypo or hyperthyroidism
Types of cardiac dysrhythmias (such as second and third degree block)
Allergy to medicinal plants
History of potassium greater than 5.1 or less than 3.5 m Eq / L at the first visit
Warfarin consumption
Pregnancy or lactation
History of hypermenorrhea in females
Presence of blood pressure greater than or equal to 180/110 mm Hg
The presence of any medical or surgical disorder that could interfere with the study.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood pressure. Timepoint: In baseline and after 4 week and after 8 week. Method of measurement: Sphygmomanometer.;FBS, BUN, Cr, TG, Cholesterol, SGOT, SGPT, CBC. Timepoint: Beginning and end of the study (after 8 weeks). Method of measurement: Biochemical and Hematological blood check.

Secondary Outcome Measures

Name	Time	Method
Quality of life score. Timepoint: pretest, post-test (at the end of 8 weeks). Method of measurement: The World Health Organization Quality of Life Questionnaire.;Stress, Anxiety and Depression score. Timepoint: pretest, post-test (at the end of 8 weeks). Method of measurement: DASS21 Questionnaire.