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临床试验/CTRI/2018/06/014630
CTRI/2018/06/014630尚未招募不适用

Dermoscopy- a useful tool for diagnosis of Pityriasis Versicolor

Kasturba Medical College1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2018年6月29日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
1
主要终点
It will help in diagnosing Pityriasis Versicolor using a non-invasive technique (dermoscopy)

研究概览

简要总结

Pityriasis versicolor is a superficial fungal infection of the skin. It is caused by Malassezia, a lipophilic dimorphic fungus. This fungus is part of the normal skin flora but can cause disease when it converts to its pathogenic hyphal form. Certain genetics and environmental factors play a role in the same. Clinically, these patients present with varied color patches which are usually covered with fine scales in seborrehic area distribution. Close differential diagnosis of tinea versicolor is confluent and reticulated papillomatosis , seborrheic dermatitis, erythrasma. Treatment line of all these conditions is different from pityriasis versicolor, hence differentiation is required. Scales over the lesions are very fine, making it difficult to examine with naked eyes, hence scraping and biopsy is usually used for confirmation of the diagnosis. Scraping of the lesions yields scales which can be mounted on microscope and fungal elements if present can be appreciated. But for confirmation biopsy with PAS stain is to be done which shows characteristic, “spaghetti and meatball†appearance.

Dermoscopy is a non-invasive tool which shows submacroscopic features of various dermatoses. It has been traditionally used in the diagnosis of melanoma is Western population. Use of dermoscopy in general dermatology practice is recently being employed. There is only one case report regarding dermoscopic features of versicolor in literature. No study has yet been published illustrating the dermoscopic features of various types of tinea versicolor. Hence, we want to carry out this study to look for a non-invasive technique to diagnose versicolor which can be done by the physician himself, bedside, within a span of few minutes.

 References –

1.       Pedrosa AF, Lisboa C, Goncalves RA. Malassezia infections: a medical conundrum. J Am Acad Dermatol. 2014;71:170-176.

2.       Renati S, Cukras A, Bigby M. Pityriasis versicolor. BMJ. 2015;350: 1394.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients suffering from Pityriasis Versicolor and ready to cooperate for study.

排除标准

  • If patient does not give consent.

结局指标

主要结局

It will help in diagnosing Pityriasis Versicolor using a non-invasive technique (dermoscopy)

时间窗: 6 months

次要结局

  • dermoscopic features of pityriasis versicolor(6 months)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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