Evaluation of Low level laser therapy against radiation induced mucositis

Not Applicable

• Conditions: Oral mucositis (ulcerative) due to radiation.; Oral mucositis (ulcerative) due to radiation; K12.33

• Registration Number: IRCT20191107045357N2
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

Patients underwent radiotherapy or chemoradiotherapy with histology-proven head and neck cancer
Receiving significant doses in all or part of the oral cavity
At least 2 separate mucosal lesions with same severity in the oral cavity with a distance of at least 3 cm
Maximum difference of half a centimeter in the diameter of the lesions

Exclusion Criteria

Serious uncontrolled systemic diseases such as diabetes, renal failure and heart failure
Vascular collagen diseases
Previous history of head and neck radiotherapy
Patients with immunodeficiency
Patients with distant metastasis
ECOG performance status more than two
Any disease or medication that interferes with the wound healing process

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of oral mucositis. Timepoint: Weekly. Method of measurement: OMAS scale.

Secondary Outcome Measures

Name	Time	Method
Pain Severity. Timepoint: Weekly. Method of measurement: VAS scale.