Efficacy of high dose doripenem on patients with severe infectious diseases in intensive care units
Not Applicable
- Conditions
- severe infectious diseases(pneumonia, bacteremia, etc)
- Registration Number
- JPRN-UMIN000009396
- Lead Sponsor
- Showa University school of medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1) more less than 16-old years 2) patients who have shown hypersensitivity to any component of beta lactams 3) non-infectious patients with fever 4) patients with causative isolates with no susceptibility to study drug (ex.MRSA, S.maltophila etc.), including metalo-beta-lactamase producing organisms 5) patients in treatment with valproic acid or with seizures and other CNS adverse experiences 6) physician's decision for adequateness in this study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical outcomes on the day of the final dosing
- Secondary Outcome Measures
Name Time Method 1)clinical outcomes on the third and the seventh day 2)duration of dosing 3)bacteriological efficacy after the final dosing 4)adverse effects and clinical examinations