Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy.

Not Applicable

Recruiting

• Conditions: Anesthesia; Epidural; Laparoscopic; Nephrectomy
• Interventions: Procedure: General Anesthesia; Procedure: Low-Thoracic Epidural Anesthesia

• Registration Number: NCT04546230
• Lead Sponsor: Nazmy Edward Seif

Brief Summary

Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay, earlier return to work and daily life activities, a more favourable cosmetic result and outcomes similar to that of open surgery.

Recently, advanced laparoscopic surgery has targeted older and high risk patients for general anesthesia; in these patients, regional anesthesia offers several advantages with improved patient satisfaction. Compared with alternative anesthetic techniques, epidural anesthesia may reduce the risks of venous thromboembolism, myocardial infarction, bleeding complications, pneumonia, respiratory depression and renal failure.

The aim of this study is to compare the conventional general anesthetic technique to the regional anesthesia for laparoscopic nephrectomy, in modified lateral decubitus position using low-pressure pneumoperitoneum.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-09-06
• Study First Submitted QC: 2020-09-06
• Study First Posted: 2020-09-11
• Study Start: 2020-09-19
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-11
• Last Update Posted: 2025-02-12
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• ASA I - II.
• Adult patients scheduled for laparoscopic nephrectomy.

Exclusion Criteria

• Patient refusal.
• Contraindication to regional anesthesia (e.g., coagulopathy, site infection).
• Allergy to local anesthetics.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
G group	General Anesthesia	General Anesthesia
E group	Low-Thoracic Epidural Anesthesia	Low-Thoracic Epidural Anesthesia

Primary Outcome Measures

Name	Time	Method
Overall patient satisfaction.	24 hours	The overall degree of patients' satisfaction will be assessed using a "5-point patient satisfaction rating scale" according to Likert scale \[where: very unsatisfied=1/5, unsatisfied=2/5, neutral=3/5, satisfied=4/5, and very satisfied=5/5\].

Trial Locations

Locations (1)

Cairo University Hospitals; 🇪🇬 Cairo, Egypt