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临床试验/NCT04546230
NCT04546230招募中不适用

Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy In Adult Patients.

Nazmy Edward Seif1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2020年9月19日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
80
试验地点
1
主要终点
Overall patient satisfaction.

研究概览

简要总结

Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay, earlier return to work and daily life activities, a more favourable cosmetic result and outcomes similar to that of open surgery.

Recently, advanced laparoscopic surgery has targeted older and high risk patients for general anesthesia; in these patients, regional anesthesia offers several advantages with improved patient satisfaction. Compared with alternative anesthetic techniques, epidural anesthesia may reduce the risks of venous thromboembolism, myocardial infarction, bleeding complications, pneumonia, respiratory depression and renal failure.

The aim of this study is to compare the conventional general anesthetic technique to the regional anesthesia for laparoscopic nephrectomy, in modified lateral decubitus position using low-pressure pneumoperitoneum.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASA I - II.
  • Adult patients scheduled for laparoscopic nephrectomy.

排除标准

  • Patient refusal.
  • Contraindication to regional anesthesia (e.g., coagulopathy, site infection).
  • Allergy to local anesthetics.

研究组 & 干预措施

E group

Experimental

Low-Thoracic Epidural Anesthesia

干预措施: Low-Thoracic Epidural Anesthesia (Procedure)

G group

Active Comparator

General Anesthesia

干预措施: General Anesthesia (Procedure)

结局指标

主要结局

Overall patient satisfaction.

时间窗: 24 hours

The overall degree of patients' satisfaction will be assessed using a "5-point patient satisfaction rating scale" according to Likert scale \[where: very unsatisfied=1/5, unsatisfied=2/5, neutral=3/5, satisfied=4/5, and very satisfied=5/5\].

次要结局

未报告次要终点

研究者

发起方
Nazmy Edward Seif
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Nazmy Edward Seif

Clinical Professor

Cairo University

研究点 (1)

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