Identification of the probable mechanisms of Duloxetine and Pregabalin involving in treatment of neuropathic pain of type 2 diabetic patients

Not Applicable

Completed

• Conditions: Condition 1: Non-insulin-dependent diabetes mellitus. Condition 2: Pain due to diabetic polyneuropathy. Condition 3: Autonomic neuropathy.; Non-insulin-dependent diabetes mellitus; Diabetic polyneuropathy; Autonomic neuropathy in endocrine and metabolic diseases; G63.2*

• Registration Number: IRCT2017012932277N1
• Lead Sponsor: The vice chancellor for research affairs of Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2018-02-22

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1-Type 2 diabetic patients with neuropathic pain which have the pain score over 4 on Visual Analogue Scale (VAS) for more than 3 months; 2-The age range: 40-60 years; 3- The patients should fill out and sign the consent forms
Exclusion criteria:
1-Hypersensitivity to Duloxetine and Pregabalin; 2-Kidney or liver failure; 3-Any other neuropathies (spinal cord injury, discopathy, congenital neuropathy, vocational, hypothyroidism, collagen vascular disease, vasculitis, Paraneoplastic disorders, immunological, alcoholism and drugs induced); 4- Rheumatoid Arthritis; 5-Goat; 6-Epilepsy; 7-Orthopedic complications; 8- Vision disability; 9-Intellectual disorders; 10-Usage of analgesic and anti-inflammatory drugs; 11-Type 1 diabetes; 12-Hypertension; 13-Smoking

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified