Phase II trial of nab-paclitaxel and carboplatin with concurrent radiotherapy for patients with locally advanced non-small cell lung cancer - Phase II trial of nab-paclitaxel and carboplatin with concurrent radiotherapy for patients with locally advanced non-small cell lung cancer

Department of Radiation Oncology, Yamaguchi University Hospital0 个研究点目标入组 37 人开始时间: 2015年11月2日最近更新: 2023年10月17日

适应症

试验速览

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•1. Patient with a history of allergy to taxane antineoplastic agents 2. Patient with a history of allergy to carboplatin or other platinum-based antineoplastic agents 3. Patient with a history of allergy to albumin 4. without the concent to the risk of infection caused by albumin preparation 5. Patients with active infection 6. Patients with serious complications (e.g. heart failure, severe pulmonary emphysema, renal disfunction, hepatic disfunction, poorly controlled diabetes or hypertension) 7. Patient with severe bone marrow suppression 8. Patient with active double cancer within 5years prior to the study 9. Patients with pleural or pericardial effusion, or ascites. 10. Patient with motor paralysis or neuropathy, except due to NSCLC 11. Exhibiting significant interstitial pneumonitis, or pulmonary fibrosis in the chest radiograph 12. Patient with collagen vascular diseases 13. Female Patient in or having a chance or planning of pregnancy or breast feeding 14. Male patient in planning to impregnate 15. Inappropriate patients for this study judged by the attending physician

发起方

Department of Radiation Oncology, Yamaguchi University Hospital