Phase II trial of nab-paclitaxel and carboplatin with concurrent radiotherapy for patients with locally advanced non-small cell lung cancer
- Conditions
- non-small cell lung cancer
- Registration Number
- JPRN-UMIN000019611
- Lead Sponsor
- Department of Radiation Oncology, Yamaguchi University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 37
Not provided
1. Patient with a history of allergy to taxane antineoplastic agents 2. Patient with a history of allergy to carboplatin or other platinum-based antineoplastic agents 3. Patient with a history of allergy to albumin 4. without the concent to the risk of infection caused by albumin preparation 5. Patients with active infection 6. Patients with serious complications (e.g. heart failure, severe pulmonary emphysema, renal disfunction, hepatic disfunction, poorly controlled diabetes or hypertension) 7. Patient with severe bone marrow suppression 8. Patient with active double cancer within 5years prior to the study 9. Patients with pleural or pericardial effusion, or ascites. 10. Patient with motor paralysis or neuropathy, except due to NSCLC 11. Exhibiting significant interstitial pneumonitis, or pulmonary fibrosis in the chest radiograph 12. Patient with collagen vascular diseases 13. Female Patient in or having a chance or planning of pregnancy or breast feeding 14. Male patient in planning to impregnate 15. Inappropriate patients for this study judged by the attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Responce Rate
- Secondary Outcome Measures
Name Time Method Completion rate of the protocol treatment, Progression Free Survival, Overall Survival, Safety, Relative Dose Intensity