A study to compare and evaluate wound healing outcome of superoxidised solution and calendula officinalis flower extract used for local wound care in patients of oral squamous cell carcinoma having postoperative wound dehiscence
Phase 3
Completed
- Registration Number
- CTRI/2022/03/041194
- Lead Sponsor
- Sharad Pawar Dental College Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
1)Patients who have undergone surgical intervention for management of oral squamous cell carcinoma(OSCC) with Neck dissection
2)Patients who have a wound dehiscence of less than equal to 2 cm² post OSCC surgery
3)Patients requiring no surgical intervention for correction of wound dehiscence.
Exclusion Criteria
1)Previous history of Radiotherapy & chemotherapy
2)Previous history of neck dissection
3)Recurrence of OSCC
4)Coagulation disorder
5)Patient unfit for surgery
6)Patients with known allergy to herbal medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)Size of wound <br/ ><br>2)Depth of wound <br/ ><br>3)Edges of wound 4)Undermining 5)Necrotic tissue type <br/ ><br>6)Necrotic tissue amount <br/ ><br>7)Exudate type <br/ ><br>8)Exudate amount in wound <br/ ><br>9)Skin color of surrounding wound. <br/ ><br>10)Peripheral tissue edema <br/ ><br>11)Peripheral tissue Induration <br/ ><br>12)Granulation tissue <br/ ><br>13)EpithelizationTimepoint: WOund dehiscence assessment on day1,5,10,15,20 post wound dehiscence
- Secondary Outcome Measures
Name Time Method Allergy to Calendula Officinalis flower extractTimepoint: On Day 1 of topical application