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临床试验/NCT02007304
NCT02007304Unknown不适用

Effects of Panax Ginseng and Salvia Miltiorrhiza Supplementation on Preventing Arterial Stiffening Effects Induced by Acute and Chronic Eccentric Exercise

National Taiwan University Hospital2 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2012年11月最近更新:
适应症

试验速览

阶段
不适用
入组人数
48
试验地点
2
主要终点
Pulse Wave Velocity

研究概览

简要总结

The purpose of is to determine the preventive effects of Chinese herb supplement with panax ginseng and salvia miltiorrhiza prior to eccentric resistance exercise on arterial stiffness and vascular reactivity by using a double-blind randomized control design and to examine the effects of a 12-week progressive eccentric resistance exercise training on arterial elasticity and vascular reactivity, and whether a long-term supplementation would ameliorate arterial stiffening effects elicited by exercise-induced inflammation and improve endothelial function.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy sedentary adults

排除标准

  • obesity (BMI >30 kg/m2)
  • smoking within past six months
  • hypertension (high blood pressure >140/90 mmHg)
  • personal history of diabetes (fasting blood glucose >126 mg/dL), heart disease, or other cardiovascular problems
  • orthopedic injury that may prevent him or her from completing the exercise
  • the use of over-the-counter supplements or vitamins

结局指标

主要结局

Pulse Wave Velocity

时间窗: 12th week of eccentric exercise training

PWV will be measured before, 6th week, 12th week of eccentric exercise training.

次要结局

  • Blood pressure(12th week of intervention)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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