Noninvasive Mapping Before Surgical Ablation

Active, not recruiting

• Conditions: Atrial Fibrillation (AF)

• Registration Number: NCT06803615
• Lead Sponsor: Medical University of Vienna

Brief Summary

The purpose of this study is to assess the electrophysiological mechanism of atrial fibrillation by means of a beat-to-beat noninvasive 3D mapping method in patients with concomitant persistent and long-standing persistent atrial fibrillation undergoing surgical ablation.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-13
• Primary Completion: 2023-03-10
• Status Verified: 2025-01
• Study First Submitted: 2025-01-27
• Study First Submitted QC: 2025-01-27
• Last Update Submitted: 2025-01-30
• Study First Posted: 2025-01-31
• Last Update Posted: 2025-02-03
• Study Completion: 2025-03

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

• legal age (18-90a)
• life expectancy > 2 years
• patients suffering from persistent and long standing atrial fibrillation
• scheduled for concomitant surgical ablation
• possibility to follow-up
• given informed consent

Exclusion Criteria

• vulnerable patient groups

• pregnancy

• any previous surgical ablation

• acute surgical indications

• any physical condition that leads to a life expectancy of less than two years

• any contraindication to the treatments necessary for the trial's conduction as e.g.

  • known allergic reaction to contrast agent
  • known allergic reaction to antiarrhythmic drugs
  • claustrophobia or anxiety in small spaces
  • severe renal impairment
  • unmanageable hyperthyroidism

• participation in any other clinical trial that either excludes enrolment or may be a confounding factor to results

• voluntary retention

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The patients electrophysiological mapping results acquired with ECGI will be analyzed: Number and distribution of rotor and focal activities will be measured.	Prior to the planned procedure.	The primary objective of this study is to measure the patients electrophysiological mapping results acquired with ECGI, namely the number and distribution of focal and rotor activities.

Trial Locations

Locations (1)

Medical University of Vienna; 🇦🇹 Vienna, Austria