Effect of Early Low Resisted Exercise With Blood Flow Restriction on Pulmonary Function in Post Cardiac Surgery Patient

Not Applicable

• Conditions: Coronary Artery Bypass Grafting; Post Coronary Artery Bypass Grafting

• Registration Number: NCT06956911
• Lead Sponsor: Cairo University

Brief Summary

After cardiac surgery Patients present a loss of exercise capacity, muscle mass, and quality of life Cardiopulmonary rehabilitation aims to reduce the loss of muscle strength, size and increase cardiopulmonary function so that quality of life is maintained as much as possible after open-heart surgeries. Traditionally, cardiac rehabilitation consist of low-intensity aerobic exercise. Therefore, cardiac rehabilitation should include not only aerobic but also resistance training (RT),. A safe and effective version of RT is needed that can still improve muscle strength and size in patients early after cardiac surgery,It is found that BFR can achieve the same result with low intensity which is suitable for patient post cardiac surgery,so the result of this study will provide a safe resisted exercise useful for post cardiac surgery patient

Detailed Description

Not available

Study Timeline

• Study Start: 2024-11-07
• Primary Completion: 2025-03-20
• Status Verified: 2025-04
• Study First Submitted: 2025-04-16
• Study First Submitted QC: 2025-04-25
• Last Update Submitted: 2025-04-25
• Study First Posted: 2025-05-04
• Last Update Posted: 2025-05-04
• Study Completion: 2025-06-15

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: Male
• Target Recruitment: 50

Inclusion Criteria

• Male patient aged from 45-60
• Elective open heart surgery via median sternotomy
• Post operative, extubated post open heart surgery, who can follow the instructions and sign the consent form
• Hemodynamic stability
• Neurological stability

Exclusion Criteria

• Still on mechanical ventilation more than 48 hours
• Neuromuscular diseases
• Rheumatoid arthritis
• Coagulopathy
• Chronic Obstructive Pulmonary Disease (COPD)
• Cardiac arrhythmias

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Hand grip strength	fourteen days	measure hand grip strength by hand held dynamometer (digital apperatus) expressed by kilogram
c-reactive protein lab	fourteen days
Functional capacity	fourteen days ,first measure will be at the session of assessment and last measure will be at the end of treatment program after fourteen days	measure functional capacity by six minute walk test by calculate the total distance covered by the patient expressed by meters
pulmonary function test, parameters that be measured is FVC and will be expressed as % of the predicted value for age,height,weight and sex and FEV1 and will be expressed as % of the predicted value of age ,sex,weight and height	fourteen days	parameters that be measured is FVC and will be expressed as % of the predicted value for age, height ,weight and sex and FEV1 and will be expressed as % of the predicted value of age ,sex, weight and height

Trial Locations

Locations (1)

National heart institute; 🇪🇬 Cairo, Egypt