A Comparative Study Of Hyperbaric Levobupivacaine 0.5% With Hyperbaric Bupivacaine 0.5% For Spinal Anaesthesia In Elective Lower Segment Cesarean Section Cases
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- To compare the effect of hyperbaric levobupivacaine 0.5% with hyperbaric bupivacaine 0.5% on :
研究概览
简要总结
Studies have been done to compare the charecteristics of both drugs .The results showed that the onset of sensory block and complete motor block was shorter in patients receiving levobupivacaine than bupivacaine.Hemodynamic stability was more with levobupivacaine.The aim of this study is to compare the anaesthetic effect and hemodynamic effects of hyperbaric levobupivacaine 0.5% with hyperbaric bupivacaine 0.5% when given in subarachnoid block in patients undergoing lower segment cesarean section.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Parturients posted for Elective Cesarean section and who give written informed consent for spinal anaesthesia.
- •2.Parturients aged between 18 years and 40 years.
排除标准
- •1.Patients refusal to participate in the study.
- •2.Contraindications to spinal anaesthesia(sepsis, local infections, spinal deformity,coagulopathies).
- •3.Period of gestation less than 35 weeks and more than 40 weeks.
- •4.Height less than155cm and more than 175cm.
- •5.BMI less than 18.5 kg/m2and more than 30 kg/m
- •6.Parturients with gestational hypertension, cardiovascular disorders and other coexisting systemic disorders.
结局指标
主要结局
To compare the effect of hyperbaric levobupivacaine 0.5% with hyperbaric bupivacaine 0.5% on :
时间窗: and at every 1minute interval for first 3 consecutive minutes followed by 5 minute intervals for the next 15minutes and at 15 minute intervals till the end of the surgery.
Sensory and motor characteristics in subarachnoid block
时间窗: and at every 1minute interval for first 3 consecutive minutes followed by 5 minute intervals for the next 15minutes and at 15 minute intervals till the end of the surgery.
次要结局
- To compare the effects of the 2 drugs on heart(rate, systolic blood pressure, diastolic blood)
研究者
Dr Madhu S N
Bangalore Medical College and Research Institute