Study of Hospital-wide Critical Respiratory Events Requiring Naloxone in a Pediatric Institution
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Opioid Induced Respiratory Depression
- Sponsor
- Children's Hospital Medical Center, Cincinnati
- Enrollment
- 95
- Locations
- 1
- Primary Endpoint
- Descriptive: Medical history and Risk Factors for critical respiratory events requiring Naloxone in children
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Opioids are the mainstay of analgesia in hospitalized children but opioid therapy is associated with life-threatening respiratory depression requiring antagonism with naloxone. Hence, it is hypothesized that naloxone requirement can be used as a quality measure of opioid safety. A retrospective medical chart review of 95 patients, who received naloxone for life threatening events, from June 2006-2012, is planned, to identify significant factors associated with risk for opioid induced respiratory depression and formulation of preventive strategies.
Investigators
Eligibility Criteria
Inclusion Criteria
- •any gender, age or race
- •administered naloxone for opioid induced respiratory depression
Exclusion Criteria
- •Any one who did not require naloxone for opioid induced respiratory depression
Outcomes
Primary Outcomes
Descriptive: Medical history and Risk Factors for critical respiratory events requiring Naloxone in children
Time Frame: about 6 hours around the event
Data leading to the event and post-event descriptives will be collected