Study of Hospital-wide Critical Respiratory Events Requiring Naloxone in a Pediatric Institution
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 95
- 试验地点
- 1
- 主要终点
- Descriptive: Medical history and Risk Factors for critical respiratory events requiring Naloxone in children
研究概览
简要总结
Opioids are the mainstay of analgesia in hospitalized children but opioid therapy is associated with life-threatening respiratory depression requiring antagonism with naloxone. Hence, it is hypothesized that naloxone requirement can be used as a quality measure of opioid safety. A retrospective medical chart review of 95 patients, who received naloxone for life threatening events, from June 2006-2012, is planned, to identify significant factors associated with risk for opioid induced respiratory depression and formulation of preventive strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Day 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •any gender, age or race
- •administered naloxone for opioid induced respiratory depression
排除标准
- •Any one who did not require naloxone for opioid induced respiratory depression
结局指标
主要结局
Descriptive: Medical history and Risk Factors for critical respiratory events requiring Naloxone in children
时间窗: about 6 hours around the event
Data leading to the event and post-event descriptives will be collected
次要结局
未报告次要终点