Assessment of effect of granulocyte colony stimulating factor (G-CSF) on immune response to vaccination against hepatitis B in patients awaiting liver transplantation.
- Conditions
- Immunity against hepatitis B viruscirrhosisOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colonInflammatory and Immune System - Normal development and function of the immune system
- Registration Number
- ACTRN12611001180909
- Lead Sponsor
- Kamran Bagheri Lankarani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Cirrhotic patients between 20 and 65 years on waiting list for liver transplantation
Exclusion Criteria
1. Previous history of viral hepatitis (HBS POSITIVE OR anti HBC Ab positive 2. HIV patients 3. Those patients who has history of vaccination 4. Patients with hepatocellular carcinoma 5. Patients with congestive heart failure (class III and IV) 6. Patients with serum creatinine >1.5 mg/dL 7. Patients with hypersensitivity to GM-CSF
8. Using immunosuppresive agents like azathioporine, tacrolimus.....
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method