Development of a Clinical and Biological Database in Peritoneal Carcinosis (BCB CARCINOSE)

Not Applicable

Recruiting

• Conditions: Cancer; Peritoneal Carcinosis
• Interventions: Biological: biological collection; Other: Tissues collections

• Registration Number: NCT04221464
• Lead Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle

Brief Summary

The creation of a prospective clinical-biological base dedicated to peritoneal carcinosis must therefore be able to serve as a support for this essential search for transfer.

Detailed Description

The main objective is to improve the knowledge of carcinosis mechanisms to develop a specific treatment.

That's why this blood collection and tissue collection is very important for the future, these collection will be permitted to the scientists to develop a research specially for carcinosis.

Study Timeline

• Study Start: 2019-11-25
• Study First Submitted: 2020-01-07
• Study First Submitted QC: 2020-01-07
• Study First Posted: 2020-01-09
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-11
• Last Update Posted: 2025-02-12
• Primary Completion: 2028-02
• Study Completion: 2038-02

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

• Patient over the age of 18;
• Patient managed for peritoneal carcinosis : digestives origins (pancreatic, gastroesophageal junction, colorectal, bowel) or peritoneum cancer
• Patient eligible for a peritoneal carcinosis treatment : at least one (or more) surgery (s) ;chemotherapy or any treatment for this disease
• Patient agree will all study procedure : biological samples & tissues samples
• Patient giving informed consent

Exclusion Criteria

• Patient not affiliated to Social Protection system
• Patient unable to understand or comply with study instructions or requirements for psychological, family, social or geographical reasons
• The level of French is insufficient to consent to the study and to response to the questionnaires
• Patient under guardianship
• Pregnancy ou breast-feeding women
• Patient treated in case of an emergency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Tumors and blood collection	Tissues collections	For all the patients include in the study : * Blood samples will be collected at different times : before any treatment, at every surgery, one month after any surgery, at progression. * Tumours and not tumours tissues will be collected at different times : Before any surgery, one month after any surgery In parallel to this biological collection, standardized clinical data will be entered into a database treatment, at every surgery
Tumors and blood collection	biological collection	For all the patients include in the study : * Blood samples will be collected at different times : before any treatment, at every surgery, one month after any surgery, at progression. * Tumours and not tumours tissues will be collected at different times : Before any surgery, one month after any surgery In parallel to this biological collection, standardized clinical data will be entered into a database treatment, at every surgery

Primary Outcome Measures

Name	Time	Method
Proportion of patients who gave their consent to participate in the study	Until the study completion: 4 years	The proportion of patients who consent to participate in the study among the screened patients

Trial Locations

Locations (1)

Institut du cancer de Montpellier ICM; 🇫🇷 Montpellier, France