Comparison of forceps biopsy and cryobiopsy in bronchoscopically visible pulmonary lesions
Not Applicable
Completed
- Conditions
- Bronchoscopically visible pulmonary lesionsCancerMalignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
- Registration Number
- ISRCTN97376650
- Lead Sponsor
- niversity Clinical Center Tuebingen (Germany) - represented by its management
- Brief Summary
2012 results in https://pubmed.ncbi.nlm.nih.gov/21852332/ (added 29/12/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 593
Inclusion Criteria
1. Clinical indication for a biopsy of an endoscopically visible endobronchial lesion suspicious for tumour
2. Aged older than 18 years, either sex
3. Signed declaration of consent
Exclusion Criteria
1. Haemorrhagic diathesis/anticoagulation
2. Oxygen saturation under 2 l/min less than 90%
3. Severe underlying cardiac disease (unstable angina pectoris, myocardial infarction in the past month, decompensated cardiac insufficiency)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensitivity of forceps biopsy versus cryobiopsy: The biopsy technique utilised was regarded as successful, when histological confirmation of the diagnosis was achieved at the initial bronchoscopy and matched the final diagnosis. If additional tests, e.g. further bronchoscopies, surgery etc. were needed to establish the tumour diagnosis, the biopsy was regarded as not diagnostic.
- Secondary Outcome Measures
Name Time Method