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Clinical Trials/ISRCTN90464927
ISRCTN90464927Completed未知

A randomised controlled trial of continuous positive airway pressure treatment in older people with obstructive sleep apnoea/hypopnoea syndrome

niversity of Oxford (UK)0 sites278 target enrollmentStarted: June 18, 2008Last updated:
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Conditions

Trial Snapshot

Phase
未知
Status
Completed
Sponsor
Enrollment
278
Study OverviewEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Sex
All

Inclusion Criteria

  • •Current inclusion criteria as of 07/04/2010:
  • •1. Aged greater than 65 years, either sex
  • •2. A clinical diagnosis of OSAHS: more than/equal to 4% oxygen desaturation index greater than 7.5 events/hour and an Epworth sleepiness scale more than/equal to 9
  • •3. Ability to give written informed consent
  • •Previous inclusion criteria at time of registration:
  • •1. Both males and females, aged greater than 65 years
  • •2. Apnoea hypopnoea index greater than or equal to 15 events/hour of sleep on multi-channel sleep study, and at least two symptoms of excessive daytime sleepiness or Epworth sleepiness scale greater than or equal to 11
  • •3. Written informed consent

Exclusion Criteria

  • •1. Previous exposure to nasal CPAP therapy
  • •2. Arterial oxygen saturation less than 93%
  • •3. Forced expiratory volume in one second (FEV1) less than 65% predicted
  • •4. Substantial problems with sleepiness driving (in those who are still driving); currently using Heavy Goods Vehicle (HGV) or Public Service Vehicle (PSV) driving licence (where applicable)
  • •5. Shift work
  • •6. Inability to give informed consent or comply with the protocol
  • •7. Irreversible visual impairment

Investigators

Sponsor
niversity of Oxford (UK)

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