Expanding Use of Continuous Glucose Monitoring Beyond COVID in Critical Care: Impact on Nurse Work Patterns and Patient Outcomes
Overview
- Phase
- Phase 1
- Intervention
- Dexcom G6
- Conditions
- Hyperglycemia
- Sponsor
- Ohio State University
- Enrollment
- 201
- Locations
- 1
- Primary Endpoint
- Percentage of Time in Target Glycemic Ranges
- Status
- Completed
- Last Updated
- 2 months ago
Overview
Brief Summary
The primary objective of this implementation study is to assess the feasibility of real time continuous glucose monitoring (CGM) implementation using a CGM plus (+) point-of-care (POC) protocol among patients on IV insulin or those with hyperglycemia (>250mg/dl) in the critical care hospital environments.
Detailed Description
This study analyzes the feasibility of inpatient real time CGM implementation through the use of a CGM + POC protocol as routine care for glycemic monitoring among patients on IV insulin or those with hyperglycemia (\>250mg/dl). The investigators will examine the effects on medical intensive care (MICU) patient's (N=100) glycemic control compared to matched historical control patients (N=100) from the MICU who received fingerstick POC.
Investigators
Eligibility Criteria
Inclusion Criteria
- •adults \>18 years old,
- •admitted to Ohio State University Wexner Medical Center MICU and
- •have hyperglycemia (glucose \>250mg/dl) or are currently on IV insulin.
Exclusion Criteria
- •Current COVID-19 infection,
- •Refractory shock (Levophed dose \>0.5 mcg/kg/min or equivalent)
- •Actively being treated for diabetic ketoacidosis (DKA)
- •Actively being treated for hyperosmolar non-ketoacidosis (HONK)
- •Pitting edema, anasarca, blue or purple discoloration to left upper extremity
- •Treated with high dose acetaminophen (\>1 gram Q6 hours)
- •Treated with hydroxyurea
- •Are pregnant, patients
- •Using home insulin pump therapy during hospitalization, or
- •Reside in a corrections institution.
Arms & Interventions
Dexcom CGM
Dexcom G6
Intervention: Dexcom G6
Historical Controls
Matched historical controls
Outcomes
Primary Outcomes
Percentage of Time in Target Glycemic Ranges
Time Frame: For duration of MICU stay which was an average of 7.6 ± 4.1 days/patient
Percent of time in target glycemic ranges: 100-180 mg/dl, 70-180mg/dl, 140-180mg/d
Secondary Outcomes
- Percent of Time in Hypoglycemic Ranges(For duration of MICU stay which was an average of 7.6 ± 4.1 days/patient)