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Clinical Trials/NCT03896022
NCT03896022
Completed
Not Applicable

Auriculotherapy as an Adjunct for Pain Management During First Trimester Vacuum Aspiration Abortion: a Randomized, Double-blinded, Three Arm Trial

Columbia University1 site in 1 country177 target enrollmentMarch 28, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Abortion in First Trimester
Sponsor
Columbia University
Enrollment
177
Locations
1
Primary Endpoint
Pain Visual Analog Scale Score (Beads vs Placebo)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Primary Objective: To assess whether usual care plus auricular acupressure with beads reduces subject-reported maximum pain during first trimester vacuum aspiration compared to usual care plus placebo.

Secondary Objective: To assess whether usual care plus auricular acupuncture with Pyonex™ needles reduces subject-reported maximum pain during first trimester vacuum aspiration as compared to usual care plus placebo. This assessment will replicate the previous trial and strengthen the evidence that auricular acupuncture is beneficial for aspiration abortion pain

Exploratory Objective: To assess whether usual care plus either auricular acupressure with beads or auricular acupuncture with Pyonex™ needles reduces subject-reported anxiety scores during first trimester vacuum aspiration as compared to women receiving usual care plus placebo.

Detailed Description

Most first trimester aspiration abortions are performed in the outpatient setting with a paracervical block and nonsteroidal anti-inflammatory drugs (NSAIDs) as the only analgesics. Yet first trimester aspiration pain control is often inadequate with 26-32% of women reporting that they experienced severe pain. Moderate sedation and general anesthesia are not readily available, and investigations on opioids and anxiolytics have consistently found them ineffective for first trimester aspiration abortion pain. In 2018, The National Academies of Sciences, Engineering, and Medicine (NASEM) recommended research to improve pain relief. Limited data indicate that acupuncture is valuable in dysmenorrhea and for labor pain, conditions in which pain may be similar to that experienced during aspiration abortion. This randomized trial will recruit women seeking first trimester aspiration abortion. This study will evaluate two types of auriculotherapy applied to selected acupoints on the external ear. The study treatments are acupressure using gold beads and acupuncture using Pyonex needles; both are applied to the ear using adhesive disks. A control group will receive the adhesive disks alone. All participants will receive usual care for their aspiration abortion procedure, including a paracervical block and ibuprofen for pain management. The investigators will query the participants regarding pain and anxiety immediately after their procedure, in person, on the day of their procedure.

Registry
clinicaltrials.gov
Start Date
March 28, 2019
End Date
December 12, 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Carolyn Westhoff

Professor of Obstetrics and Gynecology

Columbia University

Eligibility Criteria

Inclusion Criteria

  • Pregnant up to 13 weeks gestation
  • Seeking aspiration abortion for any first trimester induced abortion, abnormal pregnancy, early pregnancy loss, retained products of conception, or molar pregnancy
  • English- or Spanish-speaking
  • Willingness to be randomized into one of the three arms.

Exclusion Criteria

  • Allergy to adhesives or gold
  • Allergy or intolerance to ibuprofen or 1% lidocaine (paracervical block)
  • Congenital anomaly or infection of the ear.

Outcomes

Primary Outcomes

Pain Visual Analog Scale Score (Beads vs Placebo)

Time Frame: Immediately following the aspiration abortion procedure (approximately 10 minutes)

Self-assessed maximum pain reported using a 0-100mm visual analog scale, where 100 signifies maximum pain. To measure pain experienced during aspiration abortion.

Secondary Outcomes

  • Pain Visual Analog Scale Score (Needles vs Placebo)(Immediately following the aspiration abortion procedure (approximately 10 minutes))

Study Sites (1)

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