Association of a comprehensive geriatric assessment and toxicity, overall survival and quality of life
- Conditions
- Geriatric tumour patients receiving chemotherapy
- Registration Number
- DRKS00012532
- Lead Sponsor
- Kliniken Essen-Mitte
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 208
Inclusion Criteria
Patient with histologically confirmed carcinoma or histologically confirmed aggressive B-NHL
-First diagnosis of cancer
-Age 65 years and above
-Estimated life expectancy of at least 3 months
-Informed consent
-Judged fit or vulnerable by assessment of the geriatric-oncologic conference
OR
-Judged Unfit by assessment of the geriatric-oncologic conference
Exclusion Criteria
-Patients with leukemia, indolent lymphoma
-Previous chemotherapy
-Unwillingness of the patient to undergo a geriatric assessment
-Imminent dialysis
-Brain metastasis
-Acute coronary syndrome within the last 3 months
-Unwillingness to participate in regular follow-up visits
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of toxicity (after Common Toxicity Criteria for Adverse Events 4.0 at every visit) with regard to the assessment of the geriatric-oncologic conference after the geriatric assessment
- Secondary Outcome Measures
Name Time Method -Recognition of overall survival as a function of geriatric assessment and assessment of the geriatric-oncological conference<br>-Consideration of the quality of life (every six weeks after EORTC QLQ-C30) as a function of geriatric assessment and the assessment of the geriatric-oncologic conference<br>-Consideration of the modification of assessment parameters during cytostatic chemotherapy<br>-Assessment of a primary dose modification of chemotherapy as a function of geriatric assessment and the assessment of the geriatric-oncologic conference<br>-recognition of the rate of unfit patients who are treated by additional geriatric interventions and get fit or vulnerable as assessed of the geriatric-oncologic conference