To evaluate the IQ enhancing effect of Swarnprashana in Preschool Children

Phase 2/3

Completed

• Conditions: Appropriately healthy preschool children

• Registration Number: CTRI/2023/04/052105
• Lead Sponsor: Shri Krishna Govt Ayurvedic College and Hospital Kurukshetra Haryana

Brief Summary

v  *Swarnaprashana* preparedin this study demonstrates a range of beneficial properties including antioxidant,anti-inflammatory, antimicrobial, immunomodulatory, nootropic properties.Theseeffects contribute to promote immunity, growth and development, ultimatelyenhancingoverallhealth in children.

v  Allthe ingredients of this herbomineral prepration *Swarnaprashana*exhibitsnootropic effect and hence lead to improvement in IQ scores of the preschoolchildren when administered for continuous one month duration in the presentstudy and further stating the fact of “*Maasat Param Medhavi*†asdescribed in the ancient text by Acharya Kashyapa.

v  Totaleffect of therapy showed varied results on IQ score improvement data amongparticipants.

v  ModerateImprovement: The majority of participantsexperienced moderate gains, with 42 individuals increasing their IQ scores by1-2 points.

v  SignificantImprovement: A smaller group of 7 participants achieved significantimprovements of more than 3 points, indicating substantial cognitiveenhancement.

v  MildImprovement: Mild improvement was noted in 7 cases.

v  MarkedImprovement: Four participants demonstrated marked improvement, with increasesof 2-3 points.

v  Interestingly,none of the participants reported no improvement at all.

v  Therewas a statistically significant increase in haemoglobin levels from 11.35 ±1.07 gm% to 11.88 ± 1.09 gm% (p < 0.0001). This indicates a highlysignificant improvement in hemoglobin levels post-trial.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-07
• Study Completion: 2024-01-29
• Last Update Posted: 2024-10-19

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• 1.Healthy children of either sex belonging to age group 3 to 6 years.
• 2.Parents willing their children to participate in the trial.

Exclusion Criteria

• 1.Age below 3 years and above 6 years. 2.All congenital anomalies and all hereditary diseases. 3.Children with acute and chronic systemic infectious diseases, metabolic disorders, learning disability, Mental Retardation, Cerebral palsy. 4.All the contraindications of lehana mentioned in Kashyapa Samhita like.
• Jwara, Agnimandya, Atisara etc. 5. Subject having known history of allergy from trial drug ingredients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intelligence Quotient by Binet Kamat Test adaptation of the Stanford -Binet Test	0 day and 45th day

Secondary Outcome Measures

Name	Time	Method
Improvement in the general growth parameters of healthy pre-school going children viz. height, weight, MUAC, head circumference, chest circumference and BMI.	0 day and 45th day

Trial Locations

Locations (1)

Shri Krishna Govt. Ayurvedic College and Hospital, Kurukshetra; 🇮🇳 Kurukshetra, HARYANA, India

Shri Krishna Govt. Ayurvedic College and Hospital, Kurukshetra

🇮🇳Kurukshetra, HARYANA, India

Dr Amit Kataria

Principal investigator

9034001230

dramitkataria@rediffmail.com