Relevance of the Multiplex PCR Approach for Severe Respiratory Infections of Patients Hospitalized - Including an Intensive Care Unit, During the COVID-19 Pandemic
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Viral Pneumonia
- Sponsor
- Central Hospital, Nancy, France
- Enrollment
- 18
- Locations
- 1
- Primary Endpoint
- Occurrence of positive viral PCR assays (not COVID-19) from hospitalizations for respiratory infections.
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The hypothesis was that a retrospective investigation of the molecular virological tests in a University hospital could be informative, with the aim to identify non-COVID-19 respiratory viruses during the circulation of SARS-CoV-2, according to systematic population data for public health knowledge.
Detailed Description
The hypothesis was that a retrospective investigation of the molecular virological tests in a University hospital could be informative, with the aim to identify non-COVID-19 respiratory viruses during the circulation of SARS-CoV-2, according to systematic population data for public health knowledge: * the main goal was to perform a retrospective investigation of the molecular virological tests in a University hospital, in order to identify non-COVID-19 respiratory viruses from the beginning of 2021 to mid-2022 during the circulation of SARS-CoV-2, for public health knowledge; * the secondary aim was to retrospectively analyze, for a small subgroup of patients from an intensive care unit, the files of patients with positive molecular virological tests for non-COVID-19 respiratory viruses from the beginning of 2021 to mid-2022, reporting the following standard-of-care data: (i) the identification of the viruses, (ii) bioclinical features, (iii) medical impact of virological results in real life.
Investigators
Eligibility Criteria
Inclusion Criteria
- •For adult patients, or minors 'via' parents, able to give consent - 18 intensive care patients
Exclusion Criteria
- •Non-inclusion in case of refusal
Outcomes
Primary Outcomes
Occurrence of positive viral PCR assays (not COVID-19) from hospitalizations for respiratory infections.
Time Frame: 18 months, retrospectively
Number of patients with positive virological molecular tests (multiplex respiratory panels) from the beginning of 2021 to mid-2022, with the nature of the viruses detected and the chronology of occurrence of positive tests.
Secondary Outcomes
- Real-life features of patients in Intensive care (from the whole population - Outcome 1) with positive viral PCR during infectious pneumonia.(18 months, retrospectively)