Circadian dependence of habituation/extinction learning in exposure therapy in patients with anxiety spectrum disorders

Not Applicable

Recruiting

• Conditions: F40; F41; F42; F43.1; Phobic anxiety disorders; Other anxiety disorders; Obsessive-compulsive disorder; Post-traumatic stress disorder

• Registration Number: DRKS00031341
• Lead Sponsor: Klinikum rechts der Isar der Technischen Universität München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Anxiety disorder, obsessive-compulsive disorder, or post-traumatic stress disorder
Clinical indication for exposure therapy

Exclusion Criteria

Psychotic disorder, organic psychiatric disorder, current drug abuse or dependency, acute suicidality, pregnancy, epilepsy, clinically relevant heart or lung disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Within-session habituation (1st exposure session) as per Subjective Units of Distress (100 mm visual analogue scale) and<br>Between-session habituation (exposure sessions 1 and 2) as per Subjective Units of Distress (100 mm visual analogue scale)

Secondary Outcome Measures

Name	Time	Method
Salivary cortisol and alpha-amylase during the first two exposure sessions