Randomized controlled trial comparing skin-moisturizing agents plus pyridoxine hydrochloride with skin-moisturizing agents alone to prevent hand-foot syndrome in patients received chemotherapy of capecitabine.
Not Applicable
- Conditions
- Breast Cancer
- Registration Number
- JPRN-UMIN000002030
- Lead Sponsor
- Shikoku Cancer Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients with pervious hypersensitive reactions to component 2) regular use of pyridoxine hydrochloride 3)Regular use of levodopa 4) Patients with Grade 1 or higher hand-foot syndrome 5) Patients received chemotherapy including 5Fu 6) Patients judged as the exclusive case by the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of patients with Grade->2 hand-foot sydrome
- Secondary Outcome Measures
Name Time Method Time to the Onset of Grade=>2 hand-foot syndrome Percentage of patients with Grade=1 hand-foot syndrome