Effects of Black Tea on Type 2 Diabetes
- Conditions
- Type 2 Diabetes Mellitus
- Interventions
- Dietary Supplement: Black Tea Extract
- Registration Number
- NCT00916188
- Lead Sponsor
- National Nutrition and Food Technology Institute
- Brief Summary
The primary objective of this study is to evaluate the efficacy of different doses of black tea (150, 300, 450, 600 ml) in the test group compared to 150 ml in the control group, in improving oxidative stress, lipid profiles and insulin sensitivity.
- Detailed Description
A total of 45 patients of known T2DM (16 males and 29 females) were introduced into the controlled clinical trial and randomly assigned to either test (57.0 ± 7.9 yrs, n=23) or control (55.4 •± 8.3 yrs, n=22) group. Patients in control group were instructed to have only one cup (150 ml) of black tea/day, as a 2.5 g tea bag that had to be prepared in a standard way for one week (washout period). Patients in the test group were instructed to have 300, 450, and 600 ml (2, 3, and 4 cups, respectively) in weeks 2, 3 and 4 respectively. We assessed the change in serum glutathion, superoxidismutase, total antioxidant capacity, FBS, CRP, HbA1C, lipid profiles and fibrinogen during the end of each week.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
- Clinical diagnosis of type 2 diabetes mellitus
- Intake of antioxidant supplements during previous six months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Black Tea-Four Doses Black Tea Extract One, 2, 3 and 4 cups (150 ml/cup) of Black tea/day for week 1, 2, 3, and 4, respectively. Black Tea-One Dose Black Tea Extract One cup (150 ml) of Black tea/day during study.
- Primary Outcome Measures
Name Time Method Insulin Sensitivity, oxidative Stress, lipid Profile 4 Weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
National Nutrition and Food Technology Research Institute
🇮🇷Tehran, Iran, Islamic Republic of