The Effect of Closure Technique and Postoperative Socket Irrigation on Postoperative Complications After Impacted Mandibular Third Molar Surgery: A Randomized Controlled Trial

Phase 1

• Conditions: Postoperative complications after impacted mandibular third molar surgery in healthy human volunteers; Socket irrigation; Closure techniques; Postoperative complications; Impacted mandibular third molar

• Registration Number: TCTR20230517005
• Lead Sponsor: Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-17
• Study Completion: 2023-06-23
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

1. Patients who have non-infected impacted mandibular third molar
2. Patients who have moderate difficult impacted mandibular third molar according to Pedersons difficulty index
3. Patients who have level A or B depth impacted mandibular third molar
4. Age between 15 to 35 years old
5. Patients who have American Society of Anesthesiologist (ASA) class I or II

Exclusion Criteria

1.Patients who have more than 5 mm periodontal pocket or dental caries at distal site of adjacent mandibular second molar
2.Smoker, alcoholic, cannabis user or drug abuser
3.On drug therapy that may interfere with healing after the surgery such as glucocorticoid steroids, nonsteroidal anti-inflammatory drugs, or antibiotics
4.Pregnant women, lactating women, and patients who take oral estrogen-containing contraceptive drugs
5.Patients who have blood disorders such as Thalassemia or G6PD deficiency
6.Psychiatric patients
7.Patients who cannot participate in the study and postoperative follow-up
8.Patients who cannot follow the postoperative instructions

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity 7 Days after surgery Visual analog scale,Maximum mouth opening 7 Days after surgery millimeter,Swelling 7 Days after surgery craniometric method (millimeter),Sign of infection 30 Days after surgery presence of parameter

Secondary Outcome Measures

Name	Time	Method
Post-op complication 30 Days after surgery presence of parameter