The Development of an Artificial Intelligence Platform for Screening and Referral of Cognitive Dysfunction
Overview
- Phase
- Not Applicable
- Intervention
- Vascular dementia
- Conditions
- Eye Movement Disorder
- Sponsor
- Sun Yat-sen University
- Enrollment
- 1539
- Locations
- 1
- Primary Endpoint
- Area under the curve
- Status
- Completed
- Last Updated
- 19 days ago
Overview
Brief Summary
There is association between eye movement disorder and cognitive dysfunction. Therefore, utilizing eye movement and screening for cognitive dysfunction is feasible. In the present study, the investigators will develop an artificial intelligence platform to screening for cognitive dysfunction by inspecting the function of eye movement. Futher more, based on the screening results, the platform will offer referral suggestions.
Investigators
Haotian Lin
Professor
Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •①Subjects who are diagnosed as mild cognitive decline, Alzheimer's disease, Vascular dementia, Lewy body dementia, Frontotemporal dementia, other dementia and normal by neurologist.
- •②Subjects who can cooperate with the inspection.
- •③Subjects who agree to participate in the study and sign the consent form
Exclusion Criteria
- •①Subjects who cannot do the inspection.
- •②Subjects who suffer from diseases that compromise the inspection.
Arms & Interventions
Vascular dementia
Subjects who are diagnosed as vascular dementia(VD) according to neurologists.
Lewy body dementia
Subjects who are diagnosed as Lewy body demenita (DLB) according to neurologists.
Frontotemporal dementia
Subjects who are diagnosed as Frontotemporal demenita (FD) according to neurologists.
Other dementia
Subjects who are diagnosed as dementia but are not as AD, VD, DLB OR FD.
Normal
Subjects over 45 years old without cognitive dysfunction
Mild cognitive decline
Subjects who are diagnosed as mild cognitive decline(MCI) according to neurologists.
Alzheimer's disease
Subjects who are diagnosed as Alzheimer's disease(AD) according to neurologists.
Outcomes
Primary Outcomes
Area under the curve
Time Frame: up to 1 month
AUC values for predicting whether subject has cognitive impairment or not
Secondary Outcomes
- Accuracy, true positive rate, and true negetive rate(up to 1 month)