Register and DNA Bank of Adult Extra-hospital Sudden Death
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 2,000
- 试验地点
- 2
- 主要终点
- Identification of variants in DNA
研究概览
简要总结
The main objective of this study is the formation of a DNA bank to realise a case-control genetic study designed to identify sequence variations in DNA that predispose to sudden cardiac death in adults.
The secondary objective of this study is the creation of a register for epidemiological surveillance of adult extra-hospital sudden death.
研究设计
- 研究类型
- Interventional
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Identification of variants in DNA
The primary endpoint is the identification of variants (polymorphisms and / or mutations) in DNA significantly associated with risk of extra-hospital sudden death in adults. Study populations are : (i) the entire population of case subjects included in the DNA bank (ii) two subpopulations at high risk of sudden death : patients with a history of myocardial infarction and patients with LVEF \< 30 %. The variable analyzed is the nucleotide sequence of DNA in populations of case and control subjects.
次要结局
- Annual incidence of extra-hospital sudden death in adults
- Annual mortality related to extra-hospital sudden death in adults
- Characterization of victims of extra-hospital sudden death in adults