Study to test influence of itraconazole on blood level of cyclosporine and tacrolimus in patients after allogeneic stem cell transplantatio
Not Applicable
Recruiting
- Conditions
- Hematologic diseases
- Registration Number
- JPRN-UMIN000003240
- Lead Sponsor
- Cellular transplantation biology, Graduate School of Medical Science, Kanazawa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who meets one (or more) of each criteria as follows; 1. AST/ALT ≥5.0 x Upper Limit of Normal(ULN) 2. Bilirubin ≥2 mg/dl 3. Hypersensitivity for ITCZ 4. Glomerular filtration rate <30 ml/min 5. Use of contraindicated drug to ITCZ 6. Be disqualified by attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Create a calculating formula to predict the blood level of CyA or TAC and concentration-to-dose (C/D) ratio combined with ITCZ administration
- Secondary Outcome Measures
Name Time Method