Exercise Training in Obesity-prone Black and White Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 231
- 试验地点
- 2
- 主要终点
- Weight loss
研究概览
简要总结
Overweight premenopausal Black and White women are randomized to either diet-only, diet+aerobic or diet+resistance exercise training. Diet/behavior intervention, with or without the aerobic or resistance exercise training, will be provided throughout the 18 months of study. Major outcomes will include measures of perceived and physiologic difficulty of exercise (cardiac, ventilatory, electromyographic responses to standardized exercise tasks); aerobic fitness; strength fitness; and spontaneous free-living energy expenditure (all derived from doubly labeled water). The results will provide insight into the effectiveness of, and the mechanisms by which, different types of exercise training can improve physical fitness, spontaneous engagement in physical activities of daily living and, in turn, weight-loss maintenance.
详细描述
Overweight premenopausal Black and White women are randomized to either diet-only, diet+aerobic or diet+resistance exercise training. Diet/behavior intervention, with or without the aerobic or resistance exercise training, will be provided throughout the 18 months of study. Major outcomes will include measures of perceived and physiologic difficulty of exercise (cardiac, ventilatory, electromyographic responses to standardized exercise tasks); aerobic fitness; strength fitness; and spontaneous free-living energy expenditure (all derived from doubly labeled water). The results will provide insight into the effectiveness of, and the mechanisms by which, different types of exercise training can improve physical fitness, spontaneous engagement in physical activities of daily living and, in turn, weight-loss maintenance.
Time of initial weight loss was defined as the time needed to reach the goal of 25 kg/m2 BMI. The women will then be evaluated one year after this time and the amount of weight gain will be determined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 41 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Diet only
干预措施: Diet (Behavioral)
Diet plus aerobic exercise
干预措施: Diet (Behavioral)
Diet plus aerobic exercise
干预措施: Aerobic exercise (Behavioral)
Diet plus resistance exercise
干预措施: Diet (Behavioral)
Diet plus resistance exercise
干预措施: Resistance exercise (Behavioral)
结局指标
主要结局
Weight loss
时间窗: 6 months
Change in weight after initial weight loss
时间窗: 12 months after initial weight loss (maximum 18 months after randomization)
Time of initial weight loss determined by days to reach BMI \<= 25 (maximum 6 months)
次要结局
- Change in resting energy expenditure(18 months post baseline)
- Insulin sensitivity(18 months post baseline)
- Change in visceral fat(18 months post baseline)
- Change in cholesterol(18 months post baseline)
- Change in triglycerides(18 months post baseline)
研究者
Gary Hunter, PhD
Principle Investigator
University of Alabama at Birmingham
