An exploratory open trial to examine the safety of transplantation of autologous adipose tissue-derived stem cells for periodontal regeneration. - An exploratory open trial of transplantation of adipose tissue-derived stem cells for periodontal regeneration.

Osaka University0 sites12 target enrollmentApril 9, 2012

Overview

Phase: 未知
Intervention: Not specified
Conditions: Not specified
Sponsor: Osaka University
Enrollment: 12
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The autologous adipose tissue-derived stem cells(ADSC) were transplanted of into 12 patients, and the safety and effectiveness of periodontal regeneration by ADSC transplantation are currently being examined.

Registry

who.int

Start Date

April 9, 2012

End Date

March 31, 2019

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Osaka University

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•(1\) Persons whose clinical attachment level of experimental teeth cannot be measured. (2\) Persons who have or have had malignant tumor. (3\) Persons who are suspected to have malignant tumor or precancerous lesions at the oral cavity inspection before the registration. (4\) Persons who have administered bisphosphonates, or are to administer the drug after the registration. (5\) Persons who need to undergo the treatments, such as surgical treatment, restorative treatment or root canal treatment, which affect the experimental sites within 36 weeks after the transplantation of adipose tissue\-derived stem cells. (6\) Persons who are either pregnant, breast\-feeding or possibly pregnant by the pregnancy test before the registration, or who hope to become pregnant within 36 weeks after the transplantation of adipose tissue\-derived stem cells. (7\) Persons who suffer from disorders of kidney, liver or blood. (8\) Persons whose hemoglobinA1c is more than 6\.5% in the blood test before the entry (9\) Persons who suffer from active infectious diseases. (10\) Persons who have the history of dependence on alcohol or drugs within 6 months before the registrarion. (11\) Persons who suffer from mental or consciousness disorders. (12\) Persons who have the positive reaction to the tests for hepatitis C virus antibody, hepatitis B virus antigen, human T\-lymphotropic virus\-1 antibody or human immunodeficiency virus antibody. (13\) Persons who are judged not eligible for the subjects of this study by the principal investigator.