Partial Wrist Denervation in Comminuted Articular Distal Radius Fractures
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- The end results PAIN will be assessed according to mayo clinc wrist score
研究概览
简要总结
the aim of Partial Wrist Denervation in Comminuted articular Distal Radius Fractures is to decrease incidence of chronic wrist pain follwing this type of fracture
详细描述
Distal radius fractures represent the most common fractures in adults showing an overall prevalence of 17.5 % with respect to all fractures. partial wrist denervation is an adjunctive procedure performed during initial fracture fixation to mitigate chronic pain by interrupting sensory innervation to the wrist joint. It targets the anterior interosseous nerve (AIN) and posterior interosseous nerve (PIN), which convey nociceptive signals from the radiocarpal and midcarpal joints.
Comminuted intra-articular distal radius fractures (AO/OTA Type C2/C3) often lead to post-traumatic arthritis due to articular incongruity and capsular damage. Denervation at the index procedure may reduce central sensitization and chronic pain by resecting afferent pain fibers, potentially improving postoperative rehabilitation and functional outcomes.
Acute comminuted intra-articular distal radius fractures (AO/OTA C2/C3) with high risk of post-traumatic arthritis (e.g., articular step-off >2 mm, severe fragmentation).
- Active individuals seeking motion preservation, those with high functional demands (e.g., athletes, laborers), or patients preferring a less invasive option than salvage procedures.
- Adjunct to primary fixation: Performed concurrently with volar locking plate (VLP) or dorsal plating.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 18
- •Fracture Pattern: Acute, comminuted intra-articular distal radius fractures (AO/OTA Type C2 or C3).
- •Surgical Context: Procedure performed as a primary adjunct during initial open reduction and internal fixation (ORIF).
排除标准
- •Active local infection over the surgical site.
- •Compromised soft tissue envelope that precludes safe dissection.
- •Vascular injury or compromise requiring repair.
- •Pre-existing neurological deficit (e.g., complex regional pain syndrome, major peripheral nerve injury).
研究组 & 干预措施
parital wrist denervation
Partial Wrist Denervation in Comminuted articular Distal Radius Fractures
干预措施: Partial Wrist Denervation in Comminuted articular Distal Radius Fractures (Procedure)
结局指标
主要结局
The end results PAIN will be assessed according to mayo clinc wrist score
时间窗: 2 weeks, 6 weeks, 3 months, 6 months..and 1 year
mayo clinc wrist score its a clincal reported outcome measure designed to assess function and pain of the wrist follwing surgery the score is bassed on 100 points divided into four equally weighted categories the final score places the wrist into outcome category total score 90/100 is excellent while below 65 is poor
次要结局
未报告次要终点
研究者
Momen Moustafa
professor
Assiut University