跳至主要内容
临床试验/CTRI/2019/04/018753
CTRI/2019/04/018753招募中不适用

CORRELATION OF BRONCHOSCOPIC AND RADIOLOGICAL FINDINGS IN SUSPECTED LUNG CANCER AND ITS OUTCOME- A CROSS SECTIONAL STUDY IN A TERTIARY CARE HOSPITAL

Ramiah Medical College2 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2019年4月30日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
54
试验地点
2
主要终点
To Characterize Bronchoscopic findings in patients with Suspected Lung cancer and Correlate wit CT thorax and thereby asses positive predictive value

研究概览

简要总结

Need for the study: Bronchoscopy and computed tomography of the thorax are the most common investigations utilized to screen and diagnose lung cancer. their individual utility in diagnosing lung cancer has been demonstrated by numerous studies. Studies correlating the two modalities in Indian setup are few. Hence this study will be done to analyze the bronchoscopy findings and the radiological correlation of suspected cases of lung malignancy at our tertiary care hospital, thus asses its positive predictive value.

objectives: 1. To characterize bronchoscopic findings in patients with suspected lung cancer and correlate with CT thorax  2. To analyse the histopathological findings on biopsy

Methodology: inclusion and exclusion criteria as mentioned

All patients with suspected lung carcinoma and for whom bronchoscopy is indicated, fiber optic bronchoscopy and biopsy will be done, their bronchoscopic findings will be noted. The patient will be followed up and the Histopathological examination and IHC reports will be noted. Bronchoscopic evaluation will be done by Respiratory medicine team, CT image findings will be reported by radiologists and histopathological examination will be done by pathologists at our tertiary care centre.

Statistical analysis: descriptive statistics of confirming lung carcinoma will be analyzed and summarized in terms of percentage and its 95% confidence interval will be estimated. The diagnostic yield of bronchoscopic biopsy will be done by validating with positive predictive value.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 85.00 Year(s)(—)
性别
All

入选标准

  • clinical features suggestive of malignancy such as hemoptysis, unexplained weight loss, loss of appetite, unexplained persistent cough, hoarsnes of voice
  • Radiological features suggestive of lung malignancy 3.un explained and recurrent pleural effusion.

排除标准

  • coagulopathy,
  • platelets < 50,000/dl
  • pulmonary hypertension
  • Recent myocardial infarction or unstable angina
  • inability to cooperate during the procedure.

结局指标

主要结局

To Characterize Bronchoscopic findings in patients with Suspected Lung cancer and Correlate wit CT thorax and thereby asses positive predictive value

时间窗: 1 year 6 months

次要结局

  • To analyse the histopathological findings on biopsy(1 year 6 months)

研究者

发起方
Ramiah Medical College
申办方类型
Private medical college

研究点 (2)

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