Study on association between beta cell function and glycemic variability in the non-diabetic subjects with normal glucose tolerance and impaired glucose tolerance
Not Applicable
- Conditions
- diabetes
- Registration Number
- JPRN-UMIN000020002
- Lead Sponsor
- Kobe University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1.the use of medications that affect glucose metabolism (such as corticosteroids, beta-blockers) 2.existing or possible pregnancy 3.brestfeeding 4.an investigator's declaration that the participant was otherwise inappropriate for the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association between the parameters of glycemic variability calculated from the continuous glucose monitoring data and the index of beta cell function calculated from the data of hyperglycemic clamp and euglycemic hyperinsulinemic clamp
- Secondary Outcome Measures
Name Time Method 1.Association between the parameters of glycemic variability calculated from the continous glucose monitoring data and the index of beta cell function calculated from the date of 75g oral glucose tolerance test (75g OGTT) 2.Association between the indices of beta cell function calculated from the data of 75g OGTT and glucose clamp 3.Association between anthropometric data, serum lipid profile, basal metabolic rate measured with indirect calorimeter and the parameters of glycemic variability or the indices of beta cell function