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Effect of Prolonged Slow Expiration Technique on Blood Gases Among Pneumatic Neonates

Not Applicable
Completed
Conditions
Pneumonia
Interventions
Procedure: Traditional chest physiotherapy
Procedure: Prolonged slow expiration technique
Registration Number
NCT05781464
Lead Sponsor
Cairo University
Brief Summary

Pneumonia is a medical condition that, if not treated promptly, can lead to life- threatening complications. The prolonged slow expiration technique is a new type of chest physiotherapy that helps infants discharge bronchial secretions which accumulated due to pneumonia.

Detailed Description

Pneumonia is an infective lung condition that is one of the most common risk factors for neonatal death. Pulmonary infections, most common caused by anaerobic bacterial infection, result in the accumulation of pus in the pleural cavity. Preterms, neonates with respiratory infections, and underdeveloped lungs all require the use of a prolonged slow expiration technique.

Prolonged slow expiration technique is the only chest clearance technique that provides both effective clearance and a soothing effect. Another recommendation for this technique is lack of application of emerging techniques of respiratory physiotherapy. Although the technique is effective, it is rarely in practice over the conventional methods of chest physiotherapy.

During prolonged slow expiration, intrathoracic pressure gradually rises due to thoracoabdominal compression, preventing bronchial collapse and flow disruption that occurs during forced expirations.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
32
Inclusion Criteria
  • Age since birth till 2 months
  • Clinical findings of pneumonia: tachypnea, chest recession, fever, cyanosis and cough
  • Radiological diagnosis of pneumonia (x-ray): lober or segmental consolidation, nodular or coarse patchy infiltration, diffuse haziness and air bronchogram.
  • Neonates on oxygen therapy.
Exclusion Criteria
  • Neonates with congenital cardiopathy.
  • Neonates with surgical incision in thorax or abdomen.
  • Neonates with neurological intervention.
  • Neonates with obstruction of upper air way.
  • Neonates with gastroesophageal reflux and laryngeal affection.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Traditional chest physiotherapyTraditional chest physiotherapyThis group receives traditional chest physiotherapy that include postural drainage, percussion and vibration ( manually or by a vibrator) in each session which is twice daily from admission to neonatal intensive care unit till discharge
Prolonged slow expiration technique and traditional chest physiotherapyTraditional chest physiotherapyThis group receives traditional chest physiotherapy that include postural drainage, percussion and vibration ( manually or by a vibrator) plus prolonged slow expiration technique in each session which is twice daily from admission in neonatal intensive care unit till discharge.
Prolonged slow expiration technique and traditional chest physiotherapyProlonged slow expiration techniqueThis group receives traditional chest physiotherapy that include postural drainage, percussion and vibration ( manually or by a vibrator) plus prolonged slow expiration technique in each session which is twice daily from admission in neonatal intensive care unit till discharge.
Primary Outcome Measures
NameTimeMethod
Change in systolic and diastolic blood pressureChange from baseline systolic and diastolic blood pressure at 9 days

Systolic and diastolic blood pressure are assessed by standardized international monitor and measured by millimeters of mercury ( mmHg)

Change in bicarbonate (HCO3)Change from baseline HCO3 at 9 days

HCO3 is assessed by blood gases machine and measured by milliequivalents per litre (mEq/L) and it is used to detect electrolyte imbalance

Change in arterial oxygen saturation (Sao2)Change from Baseline SaO2 at 9 days

Arterial oxygen saturation is assessed by standardized international monitor and measured by %

Change in heart rate (HR)Change from baseline HR at 9 days

Heart rate is assessed by standardized international monitor and measured by beats per minute (BPM)

Change in temperatureChange from baseline temperature at 9 days

Temperature is assessed by thermometer and measured by degree(°)

Change in power of hydrogen (PH)Change from baseline PH at 9 days

PH is assessed by blood gases machine and it is a scale used to specify the acidity or basicity of blood

Change in partial pressure of carbon dioxide (PaCO2)Change from baseline PaCO2 at 9 days

PaCO2 is assessed by blood gases machine and measured by mmHg and it serves as a marker of sufficient alveolar ventilation within the lungs

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Faculty of physical Therapy

🇪🇬

Giza, Egypt

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