Effect of Prolonged Slow Expiration Technique on Blood Gases Among Neonates With Pneumonia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Change in systolic and diastolic blood pressure
研究概览
简要总结
Pneumonia is a medical condition that, if not treated promptly, can lead to life- threatening complications. The prolonged slow expiration technique is a new type of chest physiotherapy that helps infants discharge bronchial secretions which accumulated due to pneumonia.
详细描述
Pneumonia is an infective lung condition that is one of the most common risk factors for neonatal death. Pulmonary infections, most common caused by anaerobic bacterial infection, result in the accumulation of pus in the pleural cavity. Preterms, neonates with respiratory infections, and underdeveloped lungs all require the use of a prolonged slow expiration technique.
Prolonged slow expiration technique is the only chest clearance technique that provides both effective clearance and a soothing effect. Another recommendation for this technique is lack of application of emerging techniques of respiratory physiotherapy. Although the technique is effective, it is rarely in practice over the conventional methods of chest physiotherapy.
During prolonged slow expiration, intrathoracic pressure gradually rises due to thoracoabdominal compression, preventing bronchial collapse and flow disruption that occurs during forced expirations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 1 Day 至 2 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age since birth till 2 months
- •Clinical findings of pneumonia: tachypnea, chest recession, fever, cyanosis and cough
- •Radiological diagnosis of pneumonia (x-ray): lober or segmental consolidation, nodular or coarse patchy infiltration, diffuse haziness and air bronchogram.
- •Neonates on oxygen therapy.
排除标准
- •Neonates with congenital cardiopathy.
- •Neonates with surgical incision in thorax or abdomen.
- •Neonates with neurological intervention.
- •Neonates with obstruction of upper air way.
- •Neonates with gastroesophageal reflux and laryngeal affection.
结局指标
主要结局
Change in systolic and diastolic blood pressure
时间窗: Change from baseline systolic and diastolic blood pressure at 9 days
Systolic and diastolic blood pressure are assessed by standardized international monitor and measured by millimeters of mercury ( mmHg)
Change in bicarbonate (HCO3)
时间窗: Change from baseline HCO3 at 9 days
HCO3 is assessed by blood gases machine and measured by milliequivalents per litre (mEq/L) and it is used to detect electrolyte imbalance
Change in arterial oxygen saturation (Sao2)
时间窗: Change from Baseline SaO2 at 9 days
Arterial oxygen saturation is assessed by standardized international monitor and measured by %
Change in heart rate (HR)
时间窗: Change from baseline HR at 9 days
Heart rate is assessed by standardized international monitor and measured by beats per minute (BPM)
Change in temperature
时间窗: Change from baseline temperature at 9 days
Temperature is assessed by thermometer and measured by degree(°)
Change in power of hydrogen (PH)
时间窗: Change from baseline PH at 9 days
PH is assessed by blood gases machine and it is a scale used to specify the acidity or basicity of blood
Change in partial pressure of carbon dioxide (PaCO2)
时间窗: Change from baseline PaCO2 at 9 days
PaCO2 is assessed by blood gases machine and measured by mmHg and it serves as a marker of sufficient alveolar ventilation within the lungs
次要结局
未报告次要终点
研究者
Moshira Mohamed Metwally
Physical therapist
Cairo University