Hygiene and Bucco-dental Status of Patients With Oral Streptococcal Endocarditis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 403
- 主要终点
- Oral health status
研究概览
简要总结
Infective endocarditis (IE) is a rare (30 cases / million / year in France) and serious disease (20 % of deaths during hospitalization and 40 % after 5 years). The development of an IE results from the meeting between a bacteremia and a pre-existent heart disorder, most of the time valvular, allowing the transplant of the circulating bacteria and their multiplication in the endocardium. Recommendations of prophylactic antibiotic treatment have been established since 1954 for some medical, particularly dental procedures, at the origin of bacteremia. But this policy has recently been questioned because its efficacy has not been demonstrated.
The purpose of this study is identify the situations with risk, by comparing the oral health status and the hygiene of patients having an IE with oral streptococci to those in patients having an IE with microorganisms not of oral origin.
详细描述
It is a case-control observational study. The IE cases are recruited in hospitals participating to the french prospective observational "EI2008" cohort.
Cases are IE with oral streptococci whereas controls are IE with microorganisms not of oral origin.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major patient
- •Definite IE caused by oral streptococci (case) or by non-oral pathogens (control)
排除标准
- 未提供
结局指标
主要结局
Oral health status
时间窗: During the IE event
Dental and periodontal evaluation by a dental surgeon or a stomatologist, according to a protocol of standardized examination
次要结局
未报告次要终点
