Hygiene and Bucco-dental Status of Patients With Oral Streptococcal Endocarditis
- Conditions
- Infective Endocarditis
- Registration Number
- NCT03612245
- Lead Sponsor
- Centre Hospitalier Universitaire de Besancon
- Brief Summary
Infective endocarditis (IE) is a rare (30 cases / million / year in France) and serious disease (20 % of deaths during hospitalization and 40 % after 5 years). The development of an IE results from the meeting between a bacteremia and a pre-existent heart disorder, most of the time valvular, allowing the transplant of the circulating bacteria and their multiplication in the endocardium. Recommendations of prophylactic antibiotic treatment have been established since 1954 for some medical, particularly dental procedures, at the origin of bacteremia. But this policy has recently been questioned because its efficacy has not been demonstrated.
The purpose of this study is identify the situations with risk, by comparing the oral health status and the hygiene of patients having an IE with oral streptococci to those in patients having an IE with microorganisms not of oral origin.
- Detailed Description
It is a case-control observational study. The IE cases are recruited in hospitals participating to the french prospective observational "EI2008" cohort.
Cases are IE with oral streptococci whereas controls are IE with microorganisms not of oral origin.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 403
- Major patient
- Definite IE caused by oral streptococci (case) or by non-oral pathogens (control)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oral health status During the IE event Dental and periodontal evaluation by a dental surgeon or a stomatologist, according to a protocol of standardized examination
- Secondary Outcome Measures
Name Time Method