The Impact of Material on Microbiota in Association With Tongue and Lip Piercing
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- microbiologic findings of piercing samples
研究概览
简要总结
Biofilms on oral piercings may serve as a bacterial reservoir and lead to systemic bacteraemia or local transmission of periopathogenic microbiota.
The investigators hypothesize that there are microbiological differences in bacterial samples collected from tongue /or lip piercings made of different materials. The investigators also hypothesize that the piercings carry the same characteristic bacteria as found in the piercing channels and that independently the biofilm on the tongue/adjacent teeth is similar to the other study locations.
85 subjects with tongue and 85 subjects with lip piercing will participate. Periodontal clinical parameters, traumata of hard tissues, and characteristics of the stud are evaluated. Sterile piercings of four different materials will be randomly allocated to the study subjects. After two weeks, microbiologic samples are collected and are processed by checkerboard DNA-DNA hybridization methods.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •lip/tongue piercing for at least six month in situ
排除标准
- •pregnancy and lactating women
- •medication with known effects on gingival tissues
- •antibiotic medication in the last six months or need for antibiotic prophylaxis
- •chlorhexidine use in the last six months
- •non-plaque induced gingival disease
- •prior diagnosis of periodontitis
结局指标
主要结局
microbiologic findings of piercing samples
时间窗: 2 weeks
次要结局
- microbiologic findings in piercing channels, microbiologic findings on the tongue/adjacent teeth(2 weeks)