Study of the Immunological Profile of Archival Formalin-fixed Paraffin-embedded Solid Tumors Sample
试验速览
- 阶段
- 不适用
- 入组人数
- 1,040
- 试验地点
- 1
- 主要终点
- Immunohistochemistry scores
研究概览
简要总结
It has become clear in the recent year that the nature of the immune cells infiltrate within a tumor was essential in the control of the tumor growth. This so-called immune contexture does vary between cancer types and in response to treatments. In this context, this trial is a non-interventional, mono-centric in patients with solid tumors. Samples in paraffin-embedded material block of biopsies or surgical pieces (either primitive tumor or metastases) will be analysed. For each sample, clinically relevant data associated with treated cancer and needed for characterization of tumor microenvironment will be documented.
This trial is, through accessing to well documented selected archival tumor materials, to validate selected biomarker for early phase trial.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Sample must have had a valid written informed consent for available archival tumor samples for scientific purposes.
- •Sample from patients with histologically documented cancer in target population.
排除标准
- •Samples from subject unwilling to give their informed consent;
- •Unusable sample or biologically deteriorated.
结局指标
主要结局
Immunohistochemistry scores
时间窗: 24 months
The immunohistochemistry scores is evaluated with the score of the staining intensity. Staining Intensity: from 0 to 3 0 : no staining (absence) 1. : low staining 2. : middle staining 3. : high staining
次要结局
未报告次要终点