Effect of febuxostat on serum uric acid and renal function in patients with hyperuricemia. -open label, active (allopurinol)-controlled clinical study
Not Applicable
- Conditions
- Hyperuricemia
- Registration Number
- JPRN-UMIN000008727
- Lead Sponsor
- Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Febuxostat sensitivity (2)Hemodialysis patients (3)Secondary hyperuricemia (4)SBP>=160 or DBP>=100 (5)AST and ALT levels less than 2-times the upper limit of normal (6)Newly onset CAD and CVD within 6 months (7)Treated with mercaptopurine and azathioprine (8)During breast-feeding (9)Doctor considers inappropriate as subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change ratio of serum uric acid eGFR change from baseline
- Secondary Outcome Measures
Name Time Method