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Clinical Trials/ISRCTN87061665
ISRCTN87061665
Completed
N/A

A pilot study to determine the impact of therapeutic Human Immunodeficiency Virus (HIV) vaccination followed by a scheduled interruption of antiretroviral therapy on HIV-specific immune function by a scheduled virologic rebound in patients with prolonged viral suppression

Ottawa Hospital Research Institute (Canada)0 sites60 target enrollmentNovember 16, 2005

Overview

Phase
N/A
Intervention
Not specified
Conditions
Human Immunodeficiency Virus (HIV)
Sponsor
Ottawa Hospital Research Institute (Canada)
Enrollment
60
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
November 16, 2005
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Ottawa Hospital Research Institute (Canada)

Eligibility Criteria

Inclusion Criteria

  • 1\. HIV positive CD4 greater than 500
  • 2\. Age 18 years and older, either sex
  • 3\. CD4 nadir greater than 250
  • 4\. Viral load less than 50 for greater than 2 years
  • 5\. Receiving a Protease Inhibitor (PI) or Non\-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)

Exclusion Criteria

  • 1\. Patients with previous Acquired Immunodeficiency Syndrome (AIDS) defining opportunistic infections, previous cancer chemotherapy or other system immunosuppressive therapy
  • 2\. Patients with concurrent infections with hepatitis C or hepatitis B or any other acute illness

Outcomes

Primary Outcomes

Not specified

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