The iChill Project: can generalised anxiety disorder be prevented and treated using e-health interventions?

Completed

• Conditions: Generalised anxiety disorder; Mental and Behavioural Disorders; Other anxiety disorders

• Registration Number: ISRCTN76298775
• Lead Sponsor: Centre for Mental Health Research (CMHR) (Australia)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01-04
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 720

Inclusion Criteria

1. Aged 18 - 30 years, either sex
2. Access to the internet
3. Score 5 or higher for GAD (as assessed through GAD-7 scale)
4. Consent to participate
5. Provide active email address and phone number
6. Sufficient English language literacy

Exclusion Criteria

1. For prevention arm: meet criteria for GAD on MINI (if criteria are met, retained for treatment arm)
2. Current or previous diagnoses of psychosis, schizophrenia or bipolar disorder
3. Prevention arm: meet criteria for social phobia, panic disorder, or PTSD on MINI; treatment arm: primary diagnosis of social phobia, panic disorder, PTSD, OCD, major depression or substance dependence on ADIS-IV
4. At risk of suicide/self-harm
5. Currently on psychiatric medications
6. Currently undergoing CBT or seeing a psychologist/psychiatrist

Additional criteria for treatment arm:
7. Clinical diagnosis of GAD on ADIS-IV
8. Taking monoamine oxidase inhibitors (MAOIs) (+/- 14 days before or after treatment); concomitant pimozide
9. Treatment with sertraline in the past three months for a period of two or more weeks
10. Planning to become pregnant/pregnant/breastfeeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
GAD-7, a 7 item self-report scale measuring symptoms of GAD. In addition, for the Treatment trial any reductions in GAD diagnoses will be assessed using the Anxiety Disorders Interview Schedule-IV (ADIS-IV) (a clinician administered interview) which will be administered at assessment, post-intervention and 12 months post-intervention.