Ultrasound guided Quadratus lumborum block and Erector spinae block on Opioid sparing effect and quality of recovery in minimally invasive Nephrectomy A Prospective Randomized Comparative study

Effective pain control is an essential component of enhanced recovery after surgery, particularly in minimally invasive nephrectomy. Although laparoscopic and robotic techniques reduce surgical trauma, patients may still experience significant postoperative pain that can delay recovery and increase opioid requirements. Opioid-based analgesia, while effective, is associated with adverse effects such as nausea, vomiting, respiratory depression, and delayed mobilization, all of which can impair the quality of recovery.

In recent years, ultrasound-guided regional anesthesia techniques such as the Quadratus Lumborum Block (QLB) and the Erector Spinae Plane Block (ESPB) have emerged as promising alternatives for postoperative analgesia. Both techniques provide effective pain relief by blocking somatic and visceral pain pathways, but their relative efficacy and impact on opioid consumption and overall recovery after minimally invasive nephrectomy remain uncertain.

This prospective randomized comparative study aims to evaluate and compare the opioid-sparing effects and quality of recovery between ultrasound-guided Quadratus Lumborum Block and Erector Spinae Plane Block in patients undergoing minimally invasive nephrectomy. By identifying the more effective technique, the study seeks to contribute to improved postoperative pain management, faster recovery, and enhanced patient satisfaction while minimizing opioid-related complications.