Rectal Cancer Survivorship: Impact of Low Anterior Resection Syndrome (LARS) on the Quality of Life

Not Applicable

Completed

• Conditions: Low Anterior Resection Syndrome; Rectal Cancer

• Registration Number: NCT06059170
• Lead Sponsor: University Hospital, Ghent

Brief Summary

Quality of life and risk factors for developing major LARS are explored. Therapeutic options were explored in the cohort experiencing major LARS

Detailed Description

Quality of life and risk factors for developing major LARS are explored using the EORTC QLQ C30. Therapeutic options were explored in the cohort experiencing major LARS

Study Timeline

• Study Start: 2017-03-17
• Primary Completion: 2018-12-31
• Study Completion: 2018-12-31
• Study First Submitted: 2019-05-02
• Status Verified: 2023-09
• Study First Submitted QC: 2023-09-22
• Last Update Submitted: 2023-09-22
• Study First Posted: 2023-09-28
• Last Update Posted: 2023-09-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 187

Inclusion Criteria

• low anterior resection for rectal cancer between 2006-2016
• Adults

Exclusion Criteria

• abdomino perineal resection
• patients who do not understand Dutch

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Assessment QoL	up to 10 years after rectal resection	Assessments using questionnaire European Organization for Research and Treatment for Cancer Quality of Life Questionnaire (EORTC QLQ C30)
frequencies of therapeutic options to manage LARS	up to 10 years after rectal resection	Self developed questionaire to determine what therapeutic options were used to manage LARS
Frequency of LARS	up to 10 years after rectal resection	Assessment of LARS using validated LARS Score

Trial Locations

Locations (1)

University hospital Ghent; 🇧🇪 Ghent, Oost-Vlaanderen, Belgium