Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Length of postoperative hospital stay
研究概览
简要总结
In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits of stress block, less depression of breath. however, the epidural technique often causes more drop of blood pressure, especially in dehydrated patients. The investigators designed the trial to see if the benefit weigh out the potential risk of epidural in isolated hypertensive patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- adults aged 50-70 with isolated systolic hypertension .
排除标准
- •age < 50 yr, ASA grade IV, severe cardiac or pulmonary insufficiency (FEV1 < 1 litre) , malignant hypertension, psychiatric illness (intake of psychiatric medication other than selective serotonin re-uptake inhibitors), diastolic blood pressure more than 110 mmHg. emergency surgery, coagulopathy, significant renal and hepatic dysfunction (creatinine > 50% or liver enzymes > 50% upper limit of normal values)
结局指标
主要结局
Length of postoperative hospital stay
时间窗: 5 weeks
days
cardiovascular morbidity
时间窗: 2 weeks
case
respiratory morbidity
时间窗: 2 weeks
case
postoperative renal failure
时间窗: 2 weeks
case
次要结局
未报告次要终点
研究者
Yan Zhou, MD
MD
Peking University First Hospital
