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临床试验/NCT01884298
NCT01884298撤回不适用

Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity

Peking University First Hospital1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2013年7月2日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
撤回
入组人数
180
试验地点
1
主要终点
Length of postoperative hospital stay

研究概览

简要总结

In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits of stress block, less depression of breath. however, the epidural technique often causes more drop of blood pressure, especially in dehydrated patients. The investigators designed the trial to see if the benefit weigh out the potential risk of epidural in isolated hypertensive patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
50 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • - adults aged 50-70 with isolated systolic hypertension .

排除标准

  • age < 50 yr, ASA grade IV, severe cardiac or pulmonary insufficiency (FEV1 < 1 litre) , malignant hypertension, psychiatric illness (intake of psychiatric medication other than selective serotonin re-uptake inhibitors), diastolic blood pressure more than 110 mmHg. emergency surgery, coagulopathy, significant renal and hepatic dysfunction (creatinine > 50% or liver enzymes > 50% upper limit of normal values)

结局指标

主要结局

Length of postoperative hospital stay

时间窗: 5 weeks

days

cardiovascular morbidity

时间窗: 2 weeks

case

respiratory morbidity

时间窗: 2 weeks

case

postoperative renal failure

时间窗: 2 weeks

case

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yan Zhou, MD

MD

Peking University First Hospital

研究点 (1)

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